Select Agents and Toxins Program

Select Agents and Toxins are biological agents and toxins that have the potential to pose a severe threat to public health and safety,  to animal health, or to animal products. Select Agents and Toxins are regulated by the U.S. Department of Health and Human Services, through the Centers for Disease Control and Prevention, and the U.S. Department of Agriculture (USDA) via the Animal Plant Health Inspection Service.

The USDA Federal Select Agent Program includes Select Agents and Toxins List.

University Select Agents and Toxins Policy

To work with Select Agents or regulated quantities of Select Toxins, contact Biological Safety.

Possession of Permissible Quantities of Select Toxins

University policy requires all toxins on the Select Agents and Toxins List to be registered with the Institutional Biosafety Committee. Certain threshold limits are allowed under the regulations without full registration with the CDC


Threshold Limits

HHS Toxins [§73.3(d)(7)Amount
Abrin1000 mg
Botulinum neurotoxins1 mg
Short, paralytic alpha conotoxins100 mg
Diacetoxyscirpenol (DAS)10,000 mg
Ricin1000 mg
Saxitoxin500 mg
Staphylococcal Enterotoxins (Subtypes A, B, C, D, and E)100 mg
T-2 toxin10,000 mg
Tetrodotoxin500 mg

CDC Permissiable Toxin Amounts - Updated September 10, 2020


For details on the requirements to use non-regulated amounts of Select Toxins, refer to Appendix C in the University Select Agents Policy.

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