Biological Agents In Research

1. Bacillus anthracis
2. Brucella abortis
3. Brucella melitensis
4. Brucella suis
5. Burkholderia mallei (Pseudomonas mallei)
6. Burkholderia pseudomallei (Pseudomonas pseudomallei)
7. *Chlamydophila psittaci (formerly Chlamydia psittaci)
8. Clostridium argentinense (formerly Clostridium botulinum Type G), botulinum neurotoxin producing strains
9. Clostridium baratii, botulinum neurotoxin producing strains
10. Clostridium botulinum
11. Clostridium butyricum, botulinum neurotoxin producing strains
12. *Clostridium perfringens, epsilon toxin producing types
13. *Coccidioides immitis
14. *Coccidioides posadasii
15. Coxiella burnetii
16. Francisella tularensis
17. Mycoplasma capricolum subspecies capripneumoniae (“strain F38”)
18. Mycoplasma mycoides subspecies mycoides SC (small colony, contagious bone pleuropneumonia)
19. Rickettsia prowazekii
20. *Salmonella typhi
21. *Shiga toxin producing Eschericia coli (STEC; a.k.a. enterohaemorrhagic E. coli (EHEC) or verocytotoxin-producing E. coli (VTEC)) of serogroups O26, O45, O103, O104, O111, O121, O145, O157 and other Shiga toxin producing serogroups
22. *Shigella dysenteriae
23. *Vibrio cholera
24. Yersinia pestis

1. Abrin
2. *Aflatoxins
3. Botulinum toxins
4. *Cholera toxin
5. *Clostridium perfringens alpha, beta 1, beta 2, epsilon and iota toxins
6. Conotoxin
7. Diacetosyscirpenol toxin
8. *HT-2 toxin
9. *Microcystin (Cyanginosin)
10. *Modeccin toxin
11. Ricin$
12. Saxitoxin#$
13. *Shiga toxin
14. Staphylococcus aureus enterotoxins, hemolysin alpha toxin, and toxic shock syndrome toxin (formerly Staphylococcus enterotoxin F)
15. T-2 toxin
16. Tetrodotoxin
17. *Verotoxin and other Shiga-like ribosome inactivating proteins
18. *Viscum Ablum Lectin 1 (Viscumin)
19. *Volkensin toxin

1. Ricin in the form of Ricinus Communis AgglutininII (RCAII; aka: ricin D or Ricinus Communis LectinIII (RCLIII)) and Ricinus Communis LectinIV (RCLIV; aka ricin E).
2. The US Government must provide advance notification and annual reports to the OPWC of all exports of Schedule 1 chemicals (see 745.0 of the EAR for notification procedures).

$The following forms of saxitoxin are CWC Schedule 1 chemicals (see 742.18 of the EAR) and require a license for CW reasons to export and reexport to all destinations including Canada:

i. Saxitoxin identified by C.A.S. #35523-89-8 #While only saxitoxin is controlled on the CCL, other members of the paralytic shellfish poison family (e.g., neosaxitoxin) are designated EAR99 (see below).

ii. The US Government must provide advance notification and annual reports to the OPWC of all exports of Schedule 1 chemicals (see 745.0 of the EAR for notification procedures).

1. *Andean potato latent virus (Potato Andean latent tymovirus)
2. *Clavibacter michiganensis subspecies sepedonicus (Corynebacterium michiganensis subspecies sepedonicum or Corynebacterium sepedonicum)
3. *Cochliobolus miyabeanus (Helminthosporium oryzae)
4. *Colletotrichium kahawae (Colletotrichium coffeanum var. virulans)
5. *Magnaporthe oryzae (Pyricularia oryzae)
6. *Microcyclus ulei (Dothidella ulei)
7. Peronosclerospora philippinensis (Peronosclerospora sachhari)
8. Phoma glycinicola (formerly Pyrenochaeta glycines)
9. *Potato spindle tuber viroid
10. *Puccinia graminis ssp. Graminis var. graminis/Puccina graminis ssp. Graminis car. Stakmanii (Puccinia graminis [syn. Puccinia graminis f.sp. Tritici])
11. *Puccinia striiformis (Puccinia glumarum)
12. Ralstonia solanacearum, race 3, biovar 2 (Burkholderia solanacearum, race 3, biovar 2)
13. Rathayibacter toxicus
14. Sclerphthora rayssiae var. Zeae
15. Synchytrium endobioticum
16. *Thecaphora solani
17. *Tilletia indica
18. *Xanthomonas albilineans
19. *Xanthomonas axonopodis pv. Citri (Xanthomonas campestris pv. Citri A) (Xanthomonas campestris pv. Citri)
20. Xanthomonas oryzae

Items designated as EAR99 may be exported using the license exception "NLR", specifying "no license required", as long ALL of the following criteria are met:

1. The item is not being shipped to a sanctioned destination;
2. The item is not being shipped to a denied person, sanctioned entity or prohibited end-user; and
3. The item will not be used for a specific end-use, subject to higher controls.

Category XIV: Toxicological Agents including Chemical, Biological Agents, and Associated Equipment

MULTIPLE Export Controls, INCLUDING a License will be required to use or possess the following:

(b) Biological agents and biologically derived substances specifically developed, configured, adapted, or modified for the purpose of increasing their capability to produce casualties in humans or livestock, degrade equipment or damage crops.

(f) Equipment and its components, parts, accessories, and attachments specifically designed or modified for military operations and compatibility with military equipment as follows:

1. The dissemination, dispersion or testing of the biological agents listed in paragraph (b);
2. The detection, identification, warning or monitoring of the biological agents listed in paragraph (b);
3. Sample collection and processing of the biological agents listed in paragraph (b);
4. Individual protection against the biological agents listed in paragraph (b);
5. Collective protection against the biological agents listed in paragraph (b);
6. Decontamination or remediation of the biological agents listed in paragraph (b).

Additional items associated with, or specific to, the biological agents listed in paragraph (b) are also controlled under the ITAR including medical countermeasures (pre- and post-treatments, vaccines, antidotes, medical diagnostics); modeling or simulation tools; equipment, components, parts, accessories and attachments, exclusive of incinerators specifically designed/modified for the destruction of biological agents in paragraph (b); technical data and defense services. For more information on these items please refer to Category XIV – Toxicological Agents, including Chemical Agents, Biological Agents and Associated Equipment sections (g) through (m), page 486 ​