Comparative Pathology Shared Resource


CSPR can help you get more data from your in vivo research project by providing clinical pathology analysis of biospecimens and connecting you with research animal pathology services.

Services


CPSR hematology options are available for samples processed with EDTA or lithium heparin anticoagulant.Hematology Machine

 

  • Complete Blood Count
  • Manual differential
  • Packed cell volume (PCV)

 

Refrigerated samples are acceptable up to 7 days after collection. 

Samples must be submitted in tubes with screw top closures. Eppendorf style tubes will not be accepted.  Contact the lab for ordering information.

Hematology Stats

Any serum/plasma received with less than 50ul will receive an additional hand pipette fee.

 

Samples are good for 5 days at refrigeration, may be frozen -80c indefinitely.

 

Single Parameter Tests:


Albumin (ALB), Alkaline Phosphatase (ALP), Alanine Transaminase (ALT/GPT), Amylase (AMY), Aspartate Aminotransferase (AST/GOT), Blood Urea Nitrogen (BUN), Calcium (Ca), Creatine Kinase*(CPK), Creatinine (CRE), Gamma-glutamyl transferase (GGT), Glucose (GLU), Inorganic Phosphorus (IP), Lactate Dehydrogenase (LDH), Lipase (LIP), Ammonia*(NH3), Total Bilirubin ( Tbil), Total Carbon Dioxide*(TCO2), Total Cholesterol (T-Cho), Triglycerides (TG), Total Protein (TP), and Uric Acid (UA)

≥ 14 uL of serum (no additive) or lithium heparin plasma, each.

*Special order tests

Speciality Panel Tests:


  • 6-Chem Panel:
    • TP, ALP, GLU, ALT, CRE, BUN
      • ≥90 uL of serum (no additive) or lithium heparin plasma
  • 12-chem:
    • TP, ALB, ALP, GLU, TBIL, IP, TCHO, ALT (GPT), Ca, CRE, BUN
      • ≥ 180 uL of serum (no additive) or lithium heparin plasma.
  • Kidney function panel:
    • ALB, BUN, CRE, Ca, PHOS, TP (special order)
      • ≥90 uL of serum (no additive) or lithium heparin plasma
  • Liver function panel:
    • ALB, ALP, ALT, GGT, GLU, TBIL (special order)
      • ≥90 uL of serum (no additive) or lithium heparin plasma
  • Electrolyte panel:
    • Na, K, Cl (special order)
      • ≥ 45uL of serum (no additive) or lithium heparin plasma.

Note: average serum/plasma ratio to whole blood, is approximately 1:1 in healthy animals.

Samples must be submitted in tubes with screw-top closures. Eppendorf style tubes will not be accepted.  Contact the lab for ordering information.

Whole blood will not be accepted for blood chemistry analysis. Samples submitted must be serum or plasma.

Blood Chemistry Machine

 

Blood Chemistry Stats

Cell cytology analysis available for exudate, smear impressions, red, white and platelet cell visual inspection and cavity fluid examination.

Add cytospin technology to increase cell yield from hypocellular samples like lavage fluid or cerebrospinal fluid (CSF).

 

Cytology MicroscopeCytology Cells

 

  • Complete: Specific gravity, glucose, bilirubin, ketone, blood (hemolyzed), pH, protein, urobilinogen, nitrite, leukocyte, sedimentation exam

    ≥ .5 mL fresh urine samples should be refrigerated and analyzed day of collection

  • Partial: any combination of the above parameters.  Contact the lab to discuss order of importance.

Sedimentation examination analysis:

Urinalysis Services

Adequate and proper sample collection is critical for successful laboratory analysis. Please contact the lab for project planning assistance.

Note: collection tubes should be no larger than 1.3 mL, and submitted with a screw top closure.  Eppendorf style tubes will not be accepted.  Contact the lab for ordering information.

Hematological analysis:

  • Each analysis requires  ≥ 50uL of whole, unclotted blood collected into EDTA (preferred) or lithium heparin blood collection tubes.
  • Samples must be refrigerated (never frozen), and submitted for analysis within 7 days after collection.

Blood Chemistry Analysis:

  • Centrifugation (with removal of serum or plasma from red cell pellet), should take place within 20 minute after collection.
  • Serum or plasma must be transferred into a screw-top with non-additive tubes, refrigerated, and submitted for analysis within 5 days after collection.  
  • Serum or plasma can also be frozen at -80° for storage purposes.

12-chem≥ 180 uL of serum (no additive) or lithium heparin plasma.

 

6-chem≥90 uL of serum (no additive) or lithium heparin plasma

 

Single parameters≥ 14 uL of serum (no additive) or lithium heparin plasma, each.

 

Electrolytes: ≥ 45 uL of serum (no additive) or lithium heparin plasma.

 

Note: average serum/plasma ratio to whole blood, is approximately 1:1 in healthy animals.  Ie: one mL of whole blood will yield .5 mL serum or plasma. 

 

Urinalysis:

· Complete: Specific gravity, glucose, bilirubin, ketone, blood (hemolyzed), pH, protein, urobilinogen, nitrite, leukocyte, sedimentation exam

≥ .5 mL fresh urine submitted samples should be refrigerated and analyzed day of collection

Comparative Pathology Shared Resources Clinical Laboratory (CPSR)

Office of Laboratory Animal Resources (OLAR)

RC1 North, Anschutz Medical Campus

Contact number: 303.724.0725

Email: [email protected]

Hours: Monday - Friday 7am to 4 pm by appointment.

 

Samples must be submitted in tubes with screw top closures. Eppendorf style tubes will not be accepted. Contact the lab for ordering information. 

Assistance with sample collection is available through OLAR Veterinary Services

Contact CPSR for free project consultation with an OLAR veterinarian and customization options. Additional services may be available by request.

Clinical Pathology FY 2025-2026 Rates


Clinical Pathology Services (per sample)

ServicesCost
Single Analyte (list analyte(s) in comments)*$18.20
6-Chem (pre-surgical panel)$42.23
12-Chem (comprehensive panel)$69.67
Electrolyte Panel$23.21
Hand Sample - service fee (per sample)$12.48
Complete Blood Count (CBC)$31.62
Urinalysis & Sediment$38.67
Fecal Ova Parasite$23.21
Manual PCV$6.26
Kidney panel$53.05
Liver panel$53.05

*Please contact the lab for project management

Other services are offered

Other Services (charged per hour)

ServicesCost
Veterinarian Services$115.62/hour
Technician Services$53.13/hour

 

Not finding what you're looking for?


CMS Login