Introduced in 2025, Highlighted Topic Areas help investigators identify emerging NIH priorities and align their research with high-interest scientific areas. Researchers can submit investigator-initiated proposals through existing NIH funding opportunities while engaging early with program officers to ensure alignment and strengthen application competitiveness. Click the link below to explore all topics and their participating ICs.
Using keywords, you can search for opportunities in your area of research using Pivot-RP.
The Pivot User Guide can help you get started.
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| Title | Funder | Type | Expiration/Application | URL |
| Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers | NIH | NIMH | P50 Clinical Trial Optional | 05/19/2026 | https://grants.nih.gov/grants/guide/pa-files/PAR-24-210.html |
| Coccidioidomycosis Collaborative Research Centers | NIH | CCRC | P01 Clinical Trial Not Allowed | 07/09/2026 | https://simpler.grants.gov/opportunity/11303a9d-cdcf-4f67-9948-553ad3a7e04b |
| NHLBI Program Project Applications | NIH | NHLBI | P01 Clinical Trials Optional | 09/26/2026 | https://grants.nih.gov/grants/guide/pa-files/PAR-24-065.html |
| Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 | NIH | NCI | P50 Clinical Trial Required | 09/26/2026 | https://grants.nih.gov/grants/guide/pa-files/PAR-23-284.html |
| National Center for Construction Safety and Health Research and Translation | NIH/CDC | U54 | 12/1/2026 | https://grants.nih.gov/grants/guide/rfa-files/RFA-OH-24-001.html |
| National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorder | NIH | NIMH | U19 Clinical Trial Optional | 10/26/2027 | https://grants.nih.gov/grants/guide/pa-files/PAR-25-353.html |
| NIAID Investigator Initiated Program Project Applications | NIH | NIAID | P01 (Clinical Trial Now Allowed) | 05/25/2029 | https://simpler.grants.gov/opportunity/9b4ae9e9-8f44-494c-9f45-95774b2c84f4 |
*Note that the following forecasted funding opportunities have been recently released under a new announcement type and are only available on the Grants.gov site with limited information. If you are interested in submitting, please contact your NIH program officer and subscribe to updates using your email address under each funding opportunity.
https://grants.gov/search-grants
https://simpler.grants.gov/opportunity/328db24c-35c9-42ea-91b0-acfcb3aeb6dehttps://simpler.grants.gov/opportunity/23edd3f8-80e8-4537-b9ba-d0b852b29deb
| Funder | Type | Title | Release Date | URL |
| NIH | Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed) | 07/24/2026 | https://simpler.grants.gov/opportunity/e0cc79e9-8179-4567-9776-7dc57f4e8e3c | |
| NIH | NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System | 08/10/2026 | https://simpler.grants.gov/opportunity/9560959b-f3b5-4d8e-9306-8d87996ed72a | |
| NIH | NIDA Core "Center of Transformative Science" Grant Program | 08/18/2026 | https://simpler.grants.gov/opportunity/b5b9d054-554e-47b1-a1ba-1e302c6e6589 | |
| NIH | NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed) | 08/25/2026 | https://simpler.grants.gov/opportunity/2b529176-2d03-42a4-8057-4736a55db1be | |
| NIH | The NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) | 09/01/2026 | https://simpler.grants.gov/opportunity/7a4a9822-f39f-464d-8a1d-d941afaebcdf | |
| NIH | NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed) | 09/17/2026 | https://simpler.grants.gov/opportunity/328db24c-35c9-42ea-91b0-acfcb3aeb6de | |
| NIH | Intervention Research to Improve Native American Health | 10/22/2026 | https://simpler.grants.gov/opportunity/3a152e00-fe8e-4e29-b30e-efc659bb83dd | |
| NIH | Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed) | 11/25/2026 | https://simpler.grants.gov/opportunity/73712c84-83f0-4442-8b58-7b75836a9596 | |
| NIH | National Biomedical Research Centers (P50 Clinical Trial Optional) | 11/25/2026 | ||
| NIH | Pragmatic Trials Conducted in Health Care Systems | 11/24/2026 | https://simpler.grants.gov/opportunity/106cd2d3-4fa8-4b20-a519-4eed2b256b3c | |
| NIH | Feasibility Studies to Inform the Design of Future Clinical Trials | 11/24/2026 | https://simpler.grants.gov/opportunity/b08f815b-a840-48cb-bd2e-62caa8fd5482 | |
| NIH | Establishing a Research Network to Guide Foundational Research on Human Consciousness | 12/01/2026 | https://simpler.grants.gov/opportunity/e62cf002-ae6f-43c5-a5d2-780e7877f0c6 | |
| NIH | Claude D. Pepper Older Americans Independence Centers | 05/01/2027 | https://simpler.grants.gov/opportunity/18488b3f-1307-44af-90c9-c9bd13a857c0 | |
| NIH | A Holistic Approach to Study Non-Addictive Natural Products for Pain Management | 02/02/2027 | https://simpler.grants.gov/opportunity/bfdf98bd-f2ab-4070-bce9-fd7dedb57e31 | |
| HRSA | Pediatric Mental Health Care Access Program (PMHCA) | 5/27/2026 | https://mchb.hrsa.gov/programs-impact/programs/pediatric-mental-health-care-access | |
| CDC | NCEZID | Reducing the burden of parasitic infections in the United States through evidence-based prevention and control activities. | 6/5/2026 | ||
| NIH | UH2/UH3 Clinical Trial Not Allowed | Assay Validation of High Quality Markers for Clinical Studies in Cancer | 2/8/2027 | https://simpler.grants.gov/opportunity/d73ae356-f2bf-46e2-9838-207e1e01c400 |
| NIH | Autoimmune Diseases Statistical and Clinical Coordinating Center (AD-SCCC) | 6/4/2026 | https://simpler.grants.gov/opportunity/602e362f-6e69-4cf5-b0b7-f534cd7c3493 | |
| NIH | Pediatric and Reproductive Environmental Health Scholars (PREHS) Program | 5/23/2026 | https://simpler.grants.gov/opportunity/7088f3f8-0aad-4f2e-afa1-f53b59efa54d | |
| NIH | Limited Competition: NIGMS Mature Synchrotron Resources for Structural Biology | 10/13/2026 | https://simpler.grants.gov/opportunity/db77b347-3d04-44b2-9ecd-ad04c0d896bd |