Funding Focus Newsletter
Register for biweekly funding opportunitiesExtramural Funding Resources
Connecting researchers to published and anticipated opportunities from external federal, foundation and private sponsors.
NIH Highlighted Topics
Introduced in 2025, Highlighted Topic Areas help investigators identify emerging NIH priorities and align their research with high-interest scientific areas. Researchers can submit investigator-initiated proposals through existing NIH funding opportunities while engaging early with program officers to ensure alignment and strengthen application competitiveness. Click the link below to explore all topics and their participating ICs.
Using keywords, you can search for opportunities in your area of research using Pivot-RP.
The Pivot User Guide can help you get started.
/pivot.png?sfvrsn=f5166b4_1)
| Title | Funder | Type | Expiration/Application | URL |
| Research Centers in Minority Institutions (RCMI) Coordinating Center | NIH | U24 Clinical Trial Optional | 08/07/2026 | https://simpler.grants.gov/opportunity/8c5008f5-7daf-442a-b41c-01d25d20202e |
| Atopic Dermatitis Research Network | NIH | NIAID | U19 Clinical Trial Optional | 09/24/2026 | RFA-AI-27-004: Atopic Dermatitis Research Network (ADRN) (U19 Clinical Trial Optional) |
| Metastasis Research Network | NIH | NCI | U54 Clinical Trial Not Allowed | 09/25/2026 | RFA-CA-27-012: Metastasis Research Network (U54 Clinical Trial Not Allowed) |
| NHLBI Program Project Applications | NIH | NHLBI | P01 Clinical Trials Optional | 09/26/2026 | https://grants.nih.gov/grants/guide/pa-files/PAR-24-065.html |
| Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 | NIH | NCI | P50 Clinical Trial Required | 09/26/2026 | https://grants.nih.gov/grants/guide/pa-files/PAR-23-284.html |
| Biomedical Technology Optimization and Dissemination Center (BTOD) | NIH | NIGMS | RM1 - Clinical Trial Not Allowed | 09/29/2026 | PAR-27-024: Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed) |
| Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support | NIH | NIDA | U54 Clinical Trial Not Allowed | 09/30/2026 |
Opportunity Listing - Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed) |
| Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) | NIH | Common Fund | U54 Clinical Trial Not Allowed | 10/02/2026 | RFA-RM-27-014: Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed) |
| Nutrition Obesity Research Centers (NORCs) | NIH | NIDDK | P30 Clinical Trial Optional | 10/20/2026 | RFA-DK-27-120: Nutrition Obesity Research Centers (NORCs) (P30 Clinical Trial Optional) |
| National Center for Construction Safety and Health Research and Translation | NIH/CDC | U54 | 12/1/2026 | https://grants.nih.gov/grants/guide/rfa-files/RFA-OH-24-001.html |
| Silvio O. Conte Digestive Diseases Research Core Centers | NIH | P30 Clinical Trial Optional | 02/10/2027 |
|
| National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorder | NIH | NIMH | U19 Clinical Trial Optional | 10/26/2027 | https://grants.nih.gov/grants/guide/pa-files/PAR-25-353.html |
| NIAID Investigator Initiated Program Project Applications | NIH | NIAID | P01 (Clinical Trial Now Allowed) | 05/25/2029 | https://simpler.grants.gov/opportunity/9b4ae9e9-8f44-494c-9f45-95774b2c84f4 |
*Note that the following forecasted funding opportunities have been recently released under a new announcement type and are only available on the Grants.gov site with limited information. If you are interested in submitting, please contact your NIH program officer and subscribe to updates using your email address under each funding opportunity.
https://grants.gov/search-grants
| Funder | Type | Title | Release Date | URL |
| NIH | NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System | 08/10/2026 | https://simpler.grants.gov/opportunity/9560959b-f3b5-4d8e-9306-8d87996ed72a | |
| NIH | NIDA Core "Center of Transformative Science" Grant Program | 08/18/2026 | https://simpler.grants.gov/opportunity/b5b9d054-554e-47b1-a1ba-1e302c6e6589 | |
| NIH | NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed) | 08/25/2026 | https://simpler.grants.gov/opportunity/2b529176-2d03-42a4-8057-4736a55db1be | |
| NIH | The NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) | 09/01/2026 | https://simpler.grants.gov/opportunity/7a4a9822-f39f-464d-8a1d-d941afaebcdf | |
| NIH | Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases | 09/01/2026 | https://simpler.grants.gov/opportunity/63297aa2-31d7-48db-bf60-0be097b1e40f | |
| NIH | NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed) | 09/17/2026 | https://simpler.grants.gov/opportunity/328db24c-35c9-42ea-91b0-acfcb3aeb6de | |
| NIH | National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional) | 09/26/2026 | https://simpler.grants.gov/opportunity/3e9fb0bc-ebab-45f3-aacf-906b0ebb446c | |
| NIH | Intervention Research to Improve Native American Health | 10/22/2026 | https://simpler.grants.gov/opportunity/3a152e00-fe8e-4e29-b30e-efc659bb83dd | |
| NIH | Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development | 11/15/2026 | https://simpler.grants.gov/opportunity/6b2d1e6a-62c3-47cb-981a-53b41a59b9dd | |
| NIH | Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required) | 11/16/2026 | https://simpler.grants.gov/opportunity/23a356f5-2b12-4891-a251-d01db68c7582 | |
| NIH | Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed) | 11/25/2026 | https://simpler.grants.gov/opportunity/73712c84-83f0-4442-8b58-7b75836a9596 | |
| NIH | National Biomedical Research Centers (P50 Clinical Trial Optional) | 11/25/2026 | https://simpler.grants.gov/opportunity/23edd3f8-80e8-4537-b9ba-d0b852b29deb | |
| NIH | Pragmatic Trials Conducted in Health Care Systems | 11/24/2026 | https://simpler.grants.gov/opportunity/106cd2d3-4fa8-4b20-a519-4eed2b256b3c | |
| NIH | Feasibility Studies to Inform the Design of Future Clinical Trials | 11/24/2026 | https://simpler.grants.gov/opportunity/b08f815b-a840-48cb-bd2e-62caa8fd5482 | |
| NIH | U19 Clinical Trial Optional | NIMHD Initiative for Improving American Indian and Alaska Native Cancer Outcomes | 11/25/2026 | https://simpler.grants.gov/opportunity/fd5aaf10-314e-4a09-9978-14e7b1b283e1 |
| NIH | Establishing a Research Network to Guide Foundational Research on Human Consciousness | 12/01/2026 | https://simpler.grants.gov/opportunity/e62cf002-ae6f-43c5-a5d2-780e7877f0c6 | |
| NIH | Health Technology and ReOutcomesciprocal Innovation to Improve Clinical and Digital Public Health | 12/01/2026 | https://simpler.grants.gov/opportunity/52596a75-bd24-4f15-a996-b8fae56e392c | |
| NIH | U24 | Bridge2AI Network for AI Health Science | 01/01/2027 | https://simpler.grants.gov/opportunity/602cbc1a-d601-44f1-90d7-e6914ba594a6 |
| NIH | R61 Clinical Trial Not Allowed | Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research | 01/15/2027 | https://simpler.grants.gov/opportunity/841ce4d3-5420-4630-a9c9-6b1635c773d9 |
| NIH | R33 Clinical Trial Not Allowed | Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research | 01/17/2027 | https://simpler.grants.gov/opportunity/8747b235-c8dd-497f-a66b-9a9f5db2eb9c |
| NIH | Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed) | 02/01/2027 | https://simpler.grants.gov/opportunity/1205cb8b-2fda-44bd-b04f-11ba98a5635c | |
| NIH | BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research | 02/10/2027 | https://simpler.grants.gov/opportunity/59fa608f-e4ca-4ca9-b06c-6b499711f535 | |
| NIH | Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier | 07/24/2027 | https://simpler.grants.gov/opportunity/fcc5b681-2c2f-42d8-816d-430875a86bc3 | |
| NIH | Claude D. Pepper Older Americans Independence Centers | 05/01/2027 | https://simpler.grants.gov/opportunity/18488b3f-1307-44af-90c9-c9bd13a857c0 | |
| NIH | A Holistic Approach to Study Non-Addictive Natural Products for Pain Management | 02/02/2027 | https://simpler.grants.gov/opportunity/bfdf98bd-f2ab-4070-bce9-fd7dedb57e31 | |
| NIH | UH2/UH3 Clinical Trial Not Allowed | Assay Validation of High Quality Markers for Clinical Studies in Cancer | 2/8/2027 | https://simpler.grants.gov/opportunity/d73ae356-f2bf-46e2-9838-207e1e01c400 |
| NIH | Clinical Trial Optional | Tobacco Centers of Regulatory Science (TCORS) | 06/14/2027 | https://simpler.grants.gov/opportunity/0c2a30d6-d732-4708-9a3f-c069cb554c1f |
| NIH | Limited Competition: NIGMS Mature Synchrotron Resources for Structural Biology | 10/13/2026 | https://simpler.grants.gov/opportunity/db77b347-3d04-44b2-9ecd-ad04c0d896bd |