Volume 3, Issue 10 | June 7, 2023

Neuromuscular Training Following Concussion: A Feasibility Study Using a Virtual Platform

We are recruiting adults ages 18-40 years with a concussion history in the past 3 years for a one-time research visit.

Colorado Pulmonary Alcohol Research Consortium

We are looking for volunteers to serve as control subjects to be compared to people who drink heavily in a research project that examines substances collected from inside the lungs.

Main Procedures Involved:

• Thorough pulmonary evaluation by a lung physician by physical exam, chest x-ray, spirometry, and bronchoscopy
• Routine blood lab work & pregnancy test will be performed
  

Duration of Participation: A single study visit from 7 AM to 12 PM during a weekday.

Inhaled Cannabis, Oxidative Stress and the Pulmonary Innate Immune Response

This study evaluates the effect of long term cannabis/marijuana smoking on lung health. Volunteers should be between ages 21-55 No history of alcohol abuse, tobacco, or other recreational drug abuse No chronic medical conditions Healthy Cannabis users between ages 21 and 55 years:
1. Daily or near daily cannabis use
2. Never or limited smoking or use of inhaled tobacco products.
3. No history of chronic respiratory, cardiac, liver or renal disease

Healthy Control subjects between ages 21 and 55 years:
1. No cannabis use ever
2. Never used tobacco products
3. No history of chronic respiratory, cardiac, liver or renal disease

The Mini MED Study: Foods from the Mediterranean Diet and Health 

This study plans to learn more about how consuming a diet with foods typical to a Mediterranean Diet such as whole grains, fruits and vegetables in a Western-style diet compares to eating a typical Western-style diet. This study will look at how diet affects overall health including risk factors for heart disease, gut health and inflammation as well as underlying mechanisms linking whole food to health.

You may qualify if you: are between 30 and 69 years old, have a BMI between 25-37 kg/m2, have high blood pressure or high cholesterol, have stable medication use, have a relatively low intake of Mediterranean diet-style foods, haven’t changed your exercise patterns within the last 3 months, and do not smoke.

Main Procedures Involved:

• Monthly visits to the University of Colorado CTRC over a period of 16 weeks
• Blood, urine & stool sample collections
• Four, 4-week periods with daily consumption of various study foods such as salmon, beef, oatmeal, cheesecake, walnuts, red peppers, avocado & chickpeas
  

BURST2D Study: Breaking Up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes

We are recruiting adults ages 18-64 who have (or may have) prediabetes to participate in a physical activity intervention. Participants will be randomized to one of two interventions: ONE (45 minutes of brisk walking at least 5 days per week) and BREAK (5-minute bouts of walking 9 times a day on at least 5 days per week). We will compare the effects of each activity intervention on blood sugar and metabolism. 

A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease

Looking for subjects between ages 60 years and 85 years to verify the clinical benefit of monthly doses of aducanumab in slowing cognitive and functional impairment as measured by changes in CDR-SB score as compared with placebo in participants with early Alzheimer's disease.

IMPAACT 2021: RSV Vaccine Study 

We are looking for volunteers to participate in a blinded research study to receive either a vaccine or a placebo to help researchers learn more about how to prevent Respiratory Syncytial Virus (RSV) illness in infants and children. To join this study, your child must be 6-24 months old, have a healthy immune system, and have never had an illness caused by RSV.

Research Study on Effects of Estrogen on the Brain

The goal of this study is to understand how sex hormones, like estrogen, influence brain blood vessel function in women. Changes in heart health and blood vessel function during menopause may contribute to an increased Alzheimer’s disease risk in women. We are inviting premenopausal (women with regular menstrual periods) and postmenopausal (no menstrual period >12 months) women to participate in a study looking at the effects of estrogen and menopause on vascular function in the brain.