Volume 3, Issue 3 | February 22, 2023

A Multi-site Observational Study: NIH RECOVER Study of Long COVID in Adults

People over the age of 18 who have been diagnosed with COVID-19 in the last 30 days (PCR or rapid test--both are acceptable).

The aim is better to understand risk factors and the occurrence of PASC. Study data, including age, demographics, social determinants of health, medical history, vaccination history, details of acute SARS-CoV-2 infection, overall health and physical function, and PASC symptom screen will be reported by subjects or collected from the electronic health record using a case report form at specified intervals. Biologic specimens will be collected at specified intervals.

Skeletal Response to Simulated Night Shift (SPOTLIGHT Study)

Eligibility:

• Healthy men and women aged 20-40 years old.
• Habitually sleep 7-9 hours/night.
• Have not done night shift work in the past year.
• Do not currently smoke.
• Fully vaccinated against SARS-CoV-2

The Influence of Combined Oral Contraceptives on Weight: A 6-months Observational Study

• Female
• 18-40 years old
• BMI between 25-45
• Generally healthy
• Not currently using a hormonal form of birth control and willing to start and continue the Sprintec pill for 6 months

Cellular Airway Differences Between Asthmatics and Non-asthmatics, Obese and Non-obese Body Types

We are looking for asthmatics and non-asthmatics for a bronchoscopy study. Smoking history is ok, but you cannot actively be smoking any tobacco or marijuana in order to qualify. There will be up to 3 study visits in total, with compensation of up to $520.

How Does Inflammation Affect the Aging Brain? Research Study Investigates Aging, Memory, and Immune Function

The University of Colorado Anschutz Medical Campus is looking for interested adults 60 and over to participate in a research study examining how inflammation influences brain health. Data gathered from this study will be used to better understand how inflammation may or may not disrupt thinking and memory. Participation involves two research visits over the course of two years.
Procedures Include:

• Memory and thinking tests
• Health history questionnaires
• Blood sample
• Spinal fluid sample
• MRI of brain
• SARS-CoV-2 antibody test (results provided)

Eligibility:

• 60 years or older
• In good general health
• Have NOT been diagnosed with a memory disorder

Seeking Sedentary Women with Type 2 Diabetes

Are you interested in participating in a research study to understand the health effects of the time we spend sitting?
Inclusion Criteria:

• Women with type 2 diabetes, not being treated with insulin​​​​​
• Post-menopausal
• Non-smoker
• Not engaging in regular physical activity

Nexplanon Use in Those Primarily Choosing a Combined Oral Contraceptive: a Multicenter Trial

Taking a birth control pill or planning to? Willing to use a birth control implant too? We've got a study for that. 

ImTAB- Immunity, mTBI, and Alzheimer's Biomarkers

The University of Colorado Anschutz Medical Campus is looking for interested adults to participate in a research study examining how a concussion sustained later in life relates to inflammation and brain health. The goal of this study is to better understand how a concussion sustained later in life relates to inflammation, the aging process, and risk for future memory problems. This study involves 2 research visits: a baseline and a one year follow-up visit at the University of Colorado Anschutz Medical Campus. Compensation provided. Each Study Visit Requires:

• Health History Review
• Neurological Exam
• Thinking and memory tests
• Blood Sample
• Brain MRI

Mitoq Supplementation for Restoring Aerobic Exercise Training Effects on Endothelial Function in Postmenopausal Women

This research study aims to see if we can improve exercise training responses to heart health in postmenopausal women. We are recruiting postmenopausal women to participate in a research study to help us understand if we can enhance exercise training benefits on cardiovascular health by administering an antioxidant supplement. We are looking for postmenopausal women, age 50 years or older, with no uncontrolled high blood pressure history of cancer, diabetes, or cardiovascular disease. Participation will include 6 in-person visits lasting between 1-3 hours each – visits will occur before and after a 10-week intervention. The whole study will span approximately 14-16 weeks Compensation will be provided.

ARROW Study: Weight Loss Study

Research study looking at your body's response to dietary changes after completing a free weight loss program. You will receive: Labwork, medical exam, body composition measurements, metabolic rate results, sleep and activity assessments and free meals for two 10 day periods.

SESAD – Alzheimer’s Clinical Trial

The purpose of this research study is to learn more about the safety and effectiveness of a drug called sargramostim for improving cognitive function and memory in people with Alzheimer's disease. Participants will be asked to participate in weekly visits for 24 weeks (6 months), as well as screening and follow-up visits. Weekly appointments will be conducted at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. Compensation Provided. Study related care and medication at no cost.  These visits may include some of the following procedures:Cognitive testing, Twice weekly blood draws, Health Questionnaires, Study Partner Questionnaires, Lumbar Puncture (spinal tap), MRI, PET scan, Treatment/placebo injection 5x a week during treatment phase.
Eligibility:

• Age between 60-80 years.
• Have a diagnosis of mild-to-moderate Alzheimer's disease (AD).
• Willing and able to have a lumbar puncture (spinal tap) and twice weekly blood draws.
• Not have a first degree relative diagnosed with AD before 55 years of age.
• Have a study partner willing to give daily injections after training.