Volume 2, Issue 16 | August 17, 2022

The Parkinson's Progression Markers Initiative (PPMI) Clinical - Establishing a Deeply Phenotyped PD Cohort

Everyone age 60 and older without Parkinson's disease.

"SPOTLIGHT": Skeletal Response to Simulated Night Shift

Eligibility:

• Healthy man or woman (not pregnant) aged 20-40 years old.
• Premenopausal women must be on continuous oral contraception pills.
• Habitually sleep 7-9 hours/night.
• No night shift work in the past year.
• A non-smoker.

Firearms and Safety Messaging for Service Members

Are you a military spouse with firearms in your home or a representative from an organization that supports military families? If so, we want to hear from you! Your opinions and experiences will help us explore and develop relevant and effective strategies and messages to help prevent violence involving firearms and to help protect service members and their loved ones.

Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease (SESAD)

This research study aims to learn more about the safety and effectiveness of a drug called sargramostim for improving cognitive function and memory in people with Alzheimer's disease.
Participants will be asked to participate in weekly visits for 24 weeks (6 months), as well as screening and follow-up visits that include cognitive testing, twice weekly blood draws, heart tracing (ECG), health questionnaires, study partner questionnaires, lumbar puncture (spinal tap), MRI, PET scan and treatment/placebo injection 5x a week during the treatment phase. Health insurance is not needed for this study: study-related care and medication at no cost and compensation provided.
Eligibility:

• Be between 60-80 years old.
• Have a diagnosis of mild-to-moderate Alzheimer's disease (AD).
• Willing and able to have a lumbar puncture (spinal tap) and twice weekly blood draws.
• Have a study partner willing to give daily injections after training.

Study of IUD Expulsion with Menstrual Cup Use

Are you interested in having your IUD removed and participating in research?

Potential for the Contraceptive Implant as Emergency Contraception

To research more about ovulation (the process of egg release from the ovary) in the setting of recently placed etonogestrel implants (Nexplanon®).