Volume 3, Issue 8 | May 3, 2023

Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty

Healthy volunteers needed to study the effects of hormones on headache. Participants should be 11 - 20 years of age, male sex and male gender identity, with or without a history of headaches.

Evaluating the Peripheral Vascular Blood Flow and Oxygenation Responses to Exercise in Type 2 Diabetes with Time-Resolved, Quantitative MRI

This is a study evaluating the function of skeletal muscle and blood vessels in response to exercise  in men and women between the ages of 18-55 who may or may not have type 2 diabetes. There are a total of 4 study visits, and the study will take approximately 2 months to complete. All visits take place at the Anschutz Medical campus and each visit lasts approximately 1.5 hours. These visits will be scheduled at a time that is convenient for you but do need to take place Monday-Friday. Testing during these visits include a physical exam, blood draws, questionnaires, exercising on a stationary bike,  MRI scans of your leg and an optional cardiac MRI. Men and Women Participants 18-55 years of age are recruited under the following 3 groups:

• Lean controls: Have been weight-stable for 3 months prior to the start of the study
• Overweight controls: Have a BMI > 25 Have been weight stable for 3 months prior to start of study
• Type 2 Diabetes: Have a documented history of Type 2 Diabetes and Have been weight-stable for 3 months prior to start of study.

Inhaled Cannabis, Oxidative Stress and the Pulmonary Innate Immune Response

This study evaluates the effect of long term cannabis/marijuana smoking on lung health.
Volunteers should be between ages 21-55, No history of alcohol abuse, tobacco, or other recreational drug abuse, No chronic medical conditions.
Healthy Cannabis users between ages 21 and 55 years:

• Daily or near daily cannabis use
• Never or limited smoking or use of inhaled tobacco products.
• No history of chronic respiratory, cardiac, liver or renal disease

Healthy Control subjects between ages 21 and 55 years:

• No cannabis use ever.
• Never used tobacco products.
• No history of chronic respiratory, cardiac, liver or renal disease

A Phase 3 Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women with Uterine Fibroids or Endometriosis Who are at Risk for Pregnancy

We are seeking women who are between 18-50 years old, have endometriosis or fibroids, seeking birth control, regular menstrual cycles and BMI greater or equal to 18 kg/m2.

Healthy Starts: Introducing New Plant-Based Foods to Infants and Toddlers

The goal for this study is to understand how the timing of offering a new food repeatedly affects how much of that food your child eventually accepts and how eagerly they accept it. When you enroll, you will visit the Children's Eating Lab in Aurora 4 times over 3 months. You will offer the new food to your child at home 10 times over 6 weeks. As a participant you will receive food to offer your child and a gift card as a thank you for your time. You may be able to take part in Healthy Starts if you are at least 18 years old and you have a child between 9-12 months old, who was born full term and does not have a medical condition that makes feeding difficult.

Body Weight and Asthma: Looking at Differences in the Cellular Airway

We are looking for participants with and without asthma who would be willing to undergo a bronchoscopy procedure for research. Compensation is provided. Please see below for criteria:
We are looking for asthmatics and non-asthmatics who:

• Are between 18-65 years old
• Have a Body Mass Index (BMI) equal or greater than 30
• Have been diagnosed with asthma by a healthcare provider in case of asthmatics.
• Not  currently smoking cigarettes or marijuana and do not have a smoking history of more than 10 pack years