Volume 2, Issue 10 | May 18, 2022

Breaking Up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes

This randomized control trial examines differences in glycemia and insulin sensitivity, acute and 1-month glucose fluctuations and 1-month glucose disposal pathways between two physical activity strategies: BREAK and ONE. The BREAK strategy consists of 5-minute bouts of brisk walking performed hourly for 9 hours/day, 5 days per week, and the ONE strategy consists of a single 45-minute bout of brisk walking 5 days per week. The intervention will be maintained for two more months and glucose control will be tested. Participants will be male and female adult volunteers with overweight or obesity and pre-diabetes, a population that may be seeking physical activity options to control glucose.

Shingles Vaccine Research Study Persons Age 50 And Older

There are 4-11 visits; procedures include blood draws, administration of a challenge dose of the shingles vaccine, and may consist of a skin biopsy. The FDA-approved Shingrix vaccine will be offered at study conclusion to participants who've never received it before.

Eligibility:

• Age 50 or older.
• In general good health.
• Have never had shingles.
• Received a shingles vaccine ≥ 5 years ago and can provide documentation or never received a shingles vaccine.

Bone Health in Adults with Type 1 Diabetes

Healthy volunteers needed for research investigating bone health in adults with Type 1 diabetes. Main procedures include blood work,  bone density scans and questionnaires. Compensation will be provided.

Eligibility:

• Women >45 years and Men >50 years of age.
• HbA1C <5.7%.
• No history of Osteoporosis.
• No history of Cancer other than skin cancer.
• 4 visits over 3 years.

Colorado Pulmonary Alcohol Research Consortium

We are examining the effects of heavy alcohol and tobacco use on the development of pneumonia and serious pulmonary disease. Participation involves a thorough pulmonary evaluation by a lung physician by physical exam, chest x-ray, spirometry and bronchoscopy. We are looking for control participants: volunteers should be between ages 30-55, have no history of heavy alcohol or recreational drug abuse and no chronic medical conditions.

SANDIA: Supplementing L-Citrulline to Overweight Late Asthma oNset Phenotypes to Increase Airway L-Arginine/ADMA Ratio and Improve Asthma Control

Eligibility:

• BMI > 30kg/m2.
• Not currently smoking cigarettes.
• Not pregnant/breastfeeding or planning to get pregnant in the next 8 months.
• Take regular medication for asthma (if you are non-asthmatic this does not apply).
• Between 18 - 65 years old.
• Have been diagnosed with asthma by a healthcare provider >6 months (if you are non-asthmatic this does not apply).

Utilization of Virtual Reality Mindfulness Application to Reduce Stress and Promote Wellbeing in University Students

The National Mental Health Innovation Center is recruiting up to 75 students, residents, fellows at CU Anschutz to participate in the study. Participants will be provided with Oculus Quest or Oculus Quest 2 VR headsets for the duration of the evaluation period (8-weeks). They will be asked to complete at least one 8-10 minute TRIPP VR mindfulness session 3-5 days per week via the VR headset or their mobile phone.

Are You Interested in Having Your IUD Removed and Participating in Research?

Participation will include 1 study visit. Participation will consist of a pelvic exam, 3 transvaginal ultrasounds, and 2 menstrual cup insertions and removals.

MANATEE-T1D Study

Seeking adolescent volunteers with Type 1 Diabetes for a study to investigate how hybrid closed loop artificial pancreas systems combined with insulin sensitizing agent metformin impact blood sugar control, the body's response to insulin, and kidney and cardiovascular function when compared to individuals who are only receiving treatment with multiple daily insulin injections.

Inhaled Cannabis, Oxidative Stress and the Pulmonary Innate Immune Response

We are studying what chronic marijuana smoking does to lung health, comparing those who use marijuana to those who do not. Participation involves a thorough pulmonary evaluation by a lung physician by physical exam, chest x-ray, spirometry and bronchoscopy. Volunteers should be between ages 27-55, have no history of heavy alcohol or other recreational drug abuse and no chronic medical conditions.

Research about the Potential for the Contraceptive Implant as Emergency Contraception

Are you a healthy female between the ages of 18-40? Are you interested in starting Nexplanon®, hormonal birth control that goes in your arm?